1 Environment Toxicology Laboratory, National
Institute of Health, Department of Medical Sciences, ,Nonthaburi, Thailand.
2 Ronpibul Hospital, Nakornsithammarath,
3 Nakornsithammarath Provincial Health Office,
4 Communicable Disease Control Office (District
11) Nakornsithammarath, Thailand
5 Maharaj Hospital, Nakornsithammarath,
6 Ronpibul District Health Office, Thailand
OF ENVIRONMENTAL SCIENCE AND HEALTH Part A-Toxic/Hazardous Substances &
Environmental Engineering Vol. A38, No.1, pp. 213-221, 2003
Ronpibul village dwellers in
the southern part of Thailand have been exposed to arsenic in the water and
the environment over three generations. Over the past decades, clean water supplies,
utilization and consumption have been introduced to the area. The villagers
still use and select rainwater to other forms of potable water. In 2000, the
epidemiological survey by Siripitayakunkit (Siripitayakunlkit,U.Survey of Chronic
Arsenic Poisoning in Ronpiboon, Nakhon Si Thammarat, Thailand, 2000. Proc. 6th
International Conference on the Biochemistry of Trace Elements, Guelph, Canada)
showed prevalence rate at 24.7%, by using the skin lesion as selection criteria.
In 2000-2002, attempt to initiate the local arsenic patient center, we investigated
the population at risk in three villages. The laboratory analyses cover urine
arsenic level, urine suger screening and skin lesion classified by dermatologist.
The result showed the prevalence of 5.99% of melanosis and 8.67% of hyperkeratosis,
3.84% of urine sugar > 100 mg/dL and 6.33% urine arsenic > 50 µg/g
creatinine. There were low to negligible correlation between arsenic urine with
urine sugar (r 2 = 0.241) and arsenic urine with skin lesion
(r 2 = 0.058).